TherapeuticeffectofazithromycinonCampylobacterjejunienteritisinchildrenLIZhong-yue,MAMing,CHENJie（DepartmentofGastroenterology,AffiliatedChildren＇sHospitalofMedicalCollege,ZhejiangUniversity,Hangzhou310003,Zhejiang,China）Abstract:
ObjectivesTostudythetherapeuticeffectofazithromycinonCampylobacterjejunienteritisinchildrenandtoexplorethereasonableapplicationofantibiotics.MethodsAtotalof31casesofCampylobacterjejunienteritiswithwaterystoolwererecruitedinthestudy.Campylobacterjejuniwasdetectedbylatexagglutinationtestintheirstoolsamples.Thecaseswererandomlydividedintotwogroups.Treatmentgroup（n=17）weretreatedwithazithromycincombinedwithmucosalprotectiveagent（Smecta）andprobioticpreparation（BifidTripleViableCapsule/Powder）,Controlgroup（n=14）weretreatedbymucosalprotectiveagentandprobioticpreparationwithoutazithromycin.ThecoursesofdiseaseandthedurationofCampylobacterjejuniinthestoolwerecomparedbetweenthetwogroups.ResultsTheclinicalandbiochemicaldatabetweentwogroupswerenotsignificantlydifferent.Allthepatientsrecoveredfromtheillnesscompletely.Thecourseofdiseaseaftertherapy,totalcourseofdiseaseandthedurationofCampylobacterjejuniinstoolweresignificantlyshorterinthetreatmentgroupthancontrolgroup（P〈0.01）.ConclusionsThecourseofdiseaseandthedurationofCampylobacterjejuniinstoolareshortinchildrenwithCampylobacterjejunienteritiswhentreatedbyazithromycin..[著者文摘]
Keywords:azithromycin;waterystool;Campylobacterjejuni;enteritis
