前言目的:探讨血浆内皮素(ET)和血清一氧化氮(NO)在斑秃发病中的作用。方法:应用放射免疫法和Greiss法测定23例斑秃活动期患者、11例斑秃稳定期患者以及25例正常人血浆ET和血清NO值。结果:斑秃活动期患者ET水平和ET/NO比值显著高于正常人(P<005),但其NO水平与正常人无显著性差异(P>005);斑秃稳定期ET和NO水平以及ET/NO比值与正常人无显著性差异(P>005)。结论:斑秃活动期患者ET水平和ET/NO比值可能与斑秃的活动性有关
Objective:Toinvestigatethecorrelationbetweenexpressionofplasmaendothelin(ET)andserumnitricoxide(NO)inpatientswithalopeciaareata(AA)andclinicalseverityofthedisease.Methods:ThelevelsofplasmaETandserumNOwererespectivelydetectedbyradio-immunoassayandGreissreactionin23patientswithactiveAA,11patientswithstableAAand25normalcontrols.Results:Comparedwiththoseinnormalcontrols,thelevelsofplasmaETandET/NOinpatientswithactiveAAwerestatisticssig...