【摘要】角膜热烧伤是平时和战时常见的眼外伤,由于角膜损伤大多较为严重,治疗较为棘手,若治疗不当,预后不良。近年研究表明,药物治疗的优势体现于角膜深层结构受损前,手术治疗的优势则体现于角膜即将穿孔和穿孔后。本文拟就本病近年药物治疗和手术治疗的有关研究进展进行综述。
【关键词】角膜;热烧伤;治疗
Overviewonthetreatmentofcornealburn
YanXianLi1,BeiLi3,PingWei2
1DepartmentofOphthalmology,2DepartmentofBurn,SichuanFireArmedPoliceCorpsHospital,Chengdu610072,SichuanProvince,China;3DepartmentofOphthalmology,No.416Hospital,Chengdu610051,SichuanProvince,China
AbstractrThecornealthermalburnisacommoneyeinjuryinpeacetimeandwartime,asthemostseriouscornealdamage,itstreatmentisdifficult,anditwillleadtoapoorprognosiswithoutbeingtreatedproperly.Inrencentyearsresearchshowsthattheadvantageofthedrugstreatmentreflectsbeforethedeepstructuresdamageofcornea,andtheadvantageofthesurgeriestreatmentembodiesintheforthcomingperforationandperforationofcornea.Bothdrugsandsurgeriestreatmentsstudyprogressinrecentyearsissummarizedbelow.
rKEYWORDS:corneal;burn;treatment
LiYX,LiB,WeiP.Overviewonthetreatmentofcornealburn.Int
JOphthalmol(GuojiYankeZazhi)2008;8(11):22932295
角膜热烧伤是指高温铁水、沸油等(直接)接触性损伤角膜,或凝固汽油弹、火焰喷射等导致角膜损伤。热损伤首先累及角膜上皮细胞层及前弹力层,然后可导致基质纤维变性坏死,当损伤累及内皮细胞层则角膜发生水肿,最后直接导致角膜溃疡和穿孔,修复期则瘢痕形成并伴有新生血管长入。现就近年角膜热烧伤治疗的研究进展概述如下。