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脑神经胶质瘤病的诊断和治疗(期刊论文)

2009-11-29 www.100md.com A +

【摘要】目的探讨脑神经胶质瘤病的临床特征及其诊断与治疗。方法回顾性分析9例经开颅手术或定向活检证实为脑神经胶质瘤病的临床表现、影像学资料及治疗效果。结果9例均有颅内高压表现,CT扫描共发现23个病灶,其中病灶累及3个脑叶者5例,累及2个脑叶者4例。CT平扫病灶呈高密度5个,等密度5个,低密度13个,大多数病灶强化不明显,瘤周轻中度水肿。4例行MRI检查发现胼胝体肥大2例。9例均获得6个月以上随访。结论脑神经胶质瘤病CT扫描易误诊为转移瘤,MRI扫描对脑神经胶质瘤病的诊断有一定的价值,确诊有待于病理检查。手术切除程度是决定预后的重要因素,术后分割放疗是控制肿瘤生长及延迟复发的重要辅助治疗手段。

【关键词】肿瘤,神经上皮;诊断;治疗

Diagnosisandtreatmentofcerebralglioma

ZHENGZhipeng,GAOShujing.ThePeoplesHospitalofZhengdingCounty,Zhengding050800,China

【Abstract】ObjectiveToinvestigatetheclinicalfeatures,diagnosisandtreatmentofcerebralglioma.MethodsRetrospectiveanalysiswasconductedinviewoftheclinicalmanifestation,imaginginformationandtherapeutricresultsof9patientswithcerebralgliomaconfirmedbypathologicalexaminationafteroperationororientedbiopsy.ResultsAll9caseshadsymptomsofintracranialhypertension,and23fociwerelocatedwithCTscanning,5fociinhigherdensity,5fociinequaldensityand13fociinlowerdensity.Noenhancementdemonstratedin8foci,andslightormoderateenhancementin15foci.Allfocihandparatumoraledemaatdifferentdegrees.Thefociinvolved3lobesin5cases,and2lobesin4.MRIexaminationshowedhypertrophyofcorpuscallosumin2cases.All9caseswerefollowedupformorethanhalfayear.ConclusionCerebralgliomaispronetobemisdiagnosedasmetastatictumorbyCT,MRIscanningisvaluableforthediagnosis.Confirmeddiagnosisdependsonpathologicalexaminantion.Thedegreeofoperationalincisionisanimportantfactoraffectingprognosisandpostoperativeassistantradiotherapyisimportanttoinhibitthegrowthoftumorandpostphonetherecurrenceoftumor.......

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