前言目的:探讨上皮样血管内皮瘤的临床病理学特征。方法:对6例上皮样血管内皮瘤进行HE、组化及免疫组化(SP法)检测,1例作电镜观察。结果:年龄26~66岁,平均38岁。部位:头颈部4例,上肢、会阴各1例。形态学特征:瘤细胞似上皮细胞样,呈巢状索状管腔样排列,瘤细胞内有原始血管腔,核分裂象少见,个别病例见细胞有异型性及小灶性坏死,间质多少不一黏液样变或透明变。AB/PAS(pH10)染色5例,瘤细胞阴性,AB黏液样基质呈淡蓝色。网染显示大量血管腔隙。免疫组化检测,vimentin、CD346例均阳性,FⅧRAg、CK4例阳性,CEA、EMA、MAC3876例均阴性。电镜观察1例见胞质内含有WP小体。结论:上皮样血管内皮瘤属于低度恶性软组织肿瘤,病因不明。提高对本瘤认识可避免误诊
PurposeTostudytheclinicopathologicalfeaturesofepithelioidhemangioendothelioma(EHE).MethodsSixcasesofEHEwereexaminedwithhistologic,histochemicalandimmunohistochemicalstaining,inwhich1casewaswithultrastructuralobservation.ResultsThepatientssagerangedfrom26to66years(mean38years).EHEpresentedatavarietyofsitesincludingheadandneck(4cases),upperlimbs(1case)andperineum(1case).Themorphologicalappearanceofthetumorwascharacterizedby...