部分性脾栓塞治疗脾功能亢进推荐到首页 □黄坤明李娜曹京梅于峰兰永廷冯珉 《中国实用医药》2009年第03期1/3页123
【摘要】目的研究部分性脾栓塞治疗脾功能亢进的临床价值。方法对27例脾功能亢进患者行周围性部分性脾栓塞,栓塞剂为明胶海绵,以明胶海绵与脾动脉分支关系公式得出的明胶海绵颗粒数为基础,术中多次造影分次追加控制栓塞面积,栓塞前后测定血细胞数量。结果2例青年Child分级A级患者栓塞了75%,6例肝癌伴脾亢者为40%左右,其余均在50%~60%之间。术后24h、72h、1周、2周、4周、3个月、6个月复查血白细胞和血小板均较栓塞前明显升高(P<0.05),未出现严重并发症。结论部分性脾栓塞治疗脾功能亢进安全、显效、并发症少。术中多次造影分次追加能防止过度栓塞和栓塞不足,减轻并发症。
【关键词】脾功能亢进;栓塞
Partlysplenicembolisminthetreatmentofhypersplenism
HUANGKun-ming,LiNa,CAOJing-mei,etal.DepartmentofgastroenterologyofZiboCentralHospital,Shandong255036,China
【Abstract】ObjectiveToevaluatetheclinicalvaluationofpartlysplenicembolisminthetreatmentofhypersplenism.MethodsAllthetwenty-sevenpatienswithhypersplenismwasgivenperipheralpartlysplenicembolism,theemboluswasgelatin,thedosageofgelfoamgranulewasonthebasisoftheformationofgelatinandsplenicarterybranch.Intraoperative,multiplesplenicarteryangiographywasneeded,sotherewasaproperdosageofgelfoamgranuletocontroltheareaofsplenicembolism.pre-andpost-splenicembolism,weinvestigatethebloodrutine,espeeiallythecountofWBCandPLT.ResultsTheareaofsplenicembolismin2youngpatientswithliverfunctionChildAwas75%,in6primarylivertumorwithhypersplenismwasabout40%,andtheother’sareaofsplenicembolismwas50%~60%.Post-operative24h,72h,1week,2weeks,4weeks,3months,6months,thecountsofWBCandPLTelevatedobviouscomparedpreoperative(P<0.05),andhavenocomplications.ConclusionPartlysplenicembolisminthetreatmentofhypersplenismissafety、effective、almostnocomplication,intraoperative,multiplesplenicarteryangiographycouldcontroltheareaofsplenicembolism,preventingtheinappropriateembolism,decreasingcomplications.
【Keywords】Hypersplenism;Embolization
部分性脾栓塞(partialsplenicembolization,PSE)已广泛应用于原发性和继发性脾功能亢进的治疗,疗效肯定。2002年7月至2007年6月,笔者应用PSE治疗27例脾功能亢进患者,取得良好近期效果,报告如下。
1资料与方法
1.1一般资料本组27例,全部经临床病史、体检、实验室检查、超声或CT检查诊断为脾肿大伴脾功能亢进,脾肿大程度均为中重度,并行骨髓穿刺细胞学检查提示骨髓增生活跃。男14例,女13例;年龄26~71岁。术前外周血象:白细胞计数1.1×109~3.9×109/L;血小板计数6×109~65×109/L。肝功能Child分级A级18例、B级9例。1/3页123评论(0篇)