病理学表现:组织学上,DIP的特征是远侧气腔内过量巨噬细胞的广泛积聚,巨噬细胞分布均匀,间质受累轻。这与呼吸细支气管炎-间质性肺病不同,后者的病变明显地以细支气管为中心。大多数DIP病例与吸烟有关,但少数为特发性或伴有先天性代谢缺陷。ZMq影像园-共享放射医学资源X线胸片和CT表现:磨玻璃影为其主要异常,倾向肺周围部和基底部分布,在有些病例的磨玻璃ZMq影像园-共享放射医学资源肺区中可见微囊肿或蜂窝。ZMq影像园-共享放射医学资源
Pathology.―Histologically,DIPischaracterizedbythewidespreadaccumulationofanexcessofmacrophagesinthedistalairspaces.Themacrophagesareuniformlydistributed,unlikeinrespiratorybronchiolitisCinterstitiallungdisease,inwhichthediseaseisconspicuouslybronchiolocentric.Interstitialinvolvementisminimal.MostcasesofDIParerelatedtocigarettesmoking,butafewareidiopathicorassociatedwithrareinbornerrorsofmetabolism.ZMq影像园-共享放射医学资源
RadiographsandCTscans.―Ground-glassopacityisthedominantabnormalityandtendstohaveabasalandperipheraldistribution(Fig1).Microcysticorhoneycombchangesintheareaofground-glassopacityareseeninsomecases.ZMq影像园-共享放射医学资源
Figure1:TransverseCTscaninapatientwithdesquamativeinterstitialpneumonia.ZMq影像园-共享放射医学资源